Parkinson's disease: The quintessential neuropsychiatric disorder
Identifieur interne : 001483 ( Main/Exploration ); précédent : 001482; suivant : 001484Parkinson's disease: The quintessential neuropsychiatric disorder
Auteurs : Daniel Weintraub [États-Unis] ; David J. Burn [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-05.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Cognition Disorders (etiology), Cognition Disorders (history), Deep Brain Stimulation (methods), Dementia, Dementia (complications), Depression, History, 20th Century, History, 21st Century, Humans, Nervous system diseases, Parkinson Disease (complications), Parkinson Disease (history), Parkinson Disease (therapy), Parkinson disease, Parkinson's, Psychosis, Psychotic Disorders (etiology), Psychotic Disorders (history), dementia, depression, neuropsychiatric, psychosis.
- MESH :
- complications : Dementia, Parkinson Disease.
- etiology : Cognition Disorders, Psychotic Disorders.
- history : Cognition Disorders, Parkinson Disease, Psychotic Disorders.
- methods : Deep Brain Stimulation.
- therapy : Parkinson Disease.
- History, 20th Century, History, 21st Century, Humans.
Abstract
Although diagnosed by characteristic motor features, Parkinson's disease may be preceded, and is frequently accompanied by, a wide range of cognitive and neuropsychiatric features. In addition to the most commonly studied disorders of dementia, depression, and psychosis, other relatively common and clinically significant psychiatric complications include impulse control disorders, anxiety symptoms, disorders of sleep and wakefulness, and apathy. These problems may be underrecognized and are frequently undertreated. The emergent focus on nonmotor aspects of Parkinson's disease over the past quarter of a century is highlighted by a nonlinear increase in the number of articles published devoted to this topic. Although the development of newer antidepressants, atypical antipsychotics, and cholinesterase inhibitors in recent years has had a positive benefit on the management of these troublesome and distressing symptoms, responses are frequently suboptimal, and this remains an area of major unmet therapeutic need. © 2011 Movement Disorder Society
Url:
- https://api.istex.fr/document/8B43FCB24250ADC27534FC0218A5F01E8201250B/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513835
DOI: 10.1002/mds.23664
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Although diagnosed by characteristic motor features, Parkinson's disease may be preceded, and is frequently accompanied by, a wide range of cognitive and neuropsychiatric features. In addition to the most commonly studied disorders of dementia, depression, and psychosis, other relatively common and clinically significant psychiatric complications include impulse control disorders, anxiety symptoms, disorders of sleep and wakefulness, and apathy. These problems may be underrecognized and are frequently undertreated. The emergent focus on nonmotor aspects of Parkinson's disease over the past quarter of a century is highlighted by a nonlinear increase in the number of articles published devoted to this topic. Although the development of newer antidepressants, atypical antipsychotics, and cholinesterase inhibitors in recent years has had a positive benefit on the management of these troublesome and distressing symptoms, responses are frequently suboptimal, and this remains an area of major unmet therapeutic need. © 2011 Movement Disorder Society</div>
</front>
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